Diphenhydramine is a first-generation antihistamine widely used to relieve symptoms of allergy, hay fever, and the common cold, and is also commonly employed as a short-term sleep aid due to its sedative properties. It works by blocking histamine receptors in the brain, which helps reduce allergic reactions and induce drowsiness. Maintaining the pharmaceutical purity of Diphenhydramine is essential to ensure its safety, effectiveness, and compliance with regulatory standards. Impurity profiling is vital for detecting and controlling unwanted substances that may form during manufacturing, storage, or degradation. Here are some of its known impurities listed below.
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Catalogue No : DIPH-OCL-001
CAS No : 53499-40-4
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Synonyms
Diphenhydramine USP RC A Dimenhydrinate EP Impurity F 2-(Diphenylmethoxy)-N-methylethanamine HCl
Diphenhydramine USP RC A Dimenhydrinate EP Impurity F 2-(Diphenylmethoxy)-N-methylethanamine HCl