Mesalazine Impurities

Mesalazine, also known as mesalamine, is an anti-inflammatory drug primarily used to treat inflammatory bowel diseases such as ulcerative colitis and Crohn's disease. It works locally in the colon by inhibiting the production of inflammatory mediators like prostaglandins and leukotrienes. Maintaining the pharmaceutical purity of Mesalazine is essential to ensure its therapeutic effectiveness, minimize adverse reactions, and meet regulatory standards. Impurity profiling is crucial for detecting and controlling unwanted by-products that may arise during manufacturing, storage, or degradation. Here are some of its known impurities listed below.

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