Anastrozole is a non-steroidal aromatase inhibitor primarily used in the treatment of hormone receptor-positive breast cancer in postmenopausal women. It works by reducing estrogen levels, thereby slowing the growth of estrogen-dependent tumors. Maintaining the purity of Anastrozole is essential to ensure its therapeutic effectiveness, patient safety, and adherence to regulatory standards. Impurity profiling plays a crucial role in detecting and controlling unwanted substances that may arise during manufacturing, storage, or degradation. Here are some of its known impurities listed below.
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Catalogue No : ANAS-OCL-003
CAS No : 120511-73-1
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Synonyms
2-[3-(2-Cyano-2-propyl)-5-(1,2,4-triazol-1-ylmethyl)phenyl]-2-methyl propiononitrile
2-[3-(2-Cyano-2-propyl)-5-(1,2,4-triazol-1-ylmethyl)phenyl]-2-methyl propiononitrile

Catalogue No : ANAS-OCL-001
CAS No : 19294-04-3
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Synonyms
1,3-Bis(bromomethyl)-5-methylbenzene
1,3-Bis(bromomethyl)-5-methylbenzene

Catalogue No : ANAS-OCL-002
CAS No : 120511-74-2
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Synonyms
(3-Cyanomethyl-5-methylphenyl)acetonitrile
(3-Cyanomethyl-5-methylphenyl)acetonitrile

Catalogue No : ANAS-OCL-004
CAS No : 120512-04-1
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Synonyms
α,α,α',α'-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-benzenediacetamide
α,α,α',α'-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-benzenediacetamide

Catalogue No : ANAS-OCL-005
CAS No : 120511-84-4
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Synonyms
3,5-Bis(2-cyanoprop-2-yl)benzyl bromide
3,5-Bis(2-cyanoprop-2-yl)benzyl bromide

Catalogue No : ANAS-OCL-006
CAS No : 1027160-12-8
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Synonyms
3,5-Bis(2-cyanoprop-2-yl)bromobenzyl bromide
3,5-Bis(2-cyanoprop-2-yl)bromobenzyl bromide

Catalogue No : ANAS-OCL-007
CAS No : 120511-88-8
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Synonyms
2,2′-[5-(Hydroxymethyl)benzene-1,3-diyl]bis(2-methylpropanenitrile)
2,2′-[5-(Hydroxymethyl)benzene-1,3-diyl]bis(2-methylpropanenitrile)

Catalogue No : ANAS-OCL-008
CAS No : 120512-03-0
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Synonyms
2-(3-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2-cyanopropan-2-yl)phenyl)-2-methylpropanamide
2-(3-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2-cyanopropan-2-yl)phenyl)-2-methylpropanamide