Hydrochlorothiazide Impurities

Hydrochlorothiazide is a thiazide diuretic medication commonly used to treat high blood pressure and fluid retention (edema) associated with various medical conditions, including heart failure and kidney disorders. It works by reducing the reabsorption of sodium in the kidneys, thereby promoting the excretion of water and salts. Maintaining the pharmaceutical purity of Hydrochlorothiazide is essential to ensure its therapeutic effectiveness, minimize adverse effects, and comply with regulatory standards. Impurity profiling is crucial for detecting and controlling undesirable substances that may arise during manufacturing, storage, or degradation. Here are some of its known impurities listed below.

Hydrochlorothiazide

Catalogue No : HYDR-OCL-001

CAS No : 58-93-5

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Synonyms
6-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide

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Hydrochlorothiazide 5-Chloro Impurity

Catalogue No : HYDR-OCL-002

CAS No : 5233-42-1

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Synonyms
5,6-Dichloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide

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Hydrochlorothiazide Impurity 1

Catalogue No : HYDR-OCL-006

CAS No : 1329838-65-4

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Synonyms
4-Amino-5,6-dichlorobenzene-1,3-disulfonamide hydrochloride

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Hydrochlorothiazide Impurity A

Catalogue No : HYDR-OCL-003

CAS No : 58-94-6

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Synonyms
6-Chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide

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Hydrochlorothiazide Impurity B

Catalogue No : HYDR-OCL-004

CAS No : 121-30-2

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Synonyms
4-Amino-6-chlorobenzene-1,3-disulfonamide

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Hydrochlorothiazide Impurity C

Catalogue No : HYDR-OCL-005

CAS No : 402824-96-8

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Synonyms
6-Chloro-N-[(6-chloro-7-sulfamoyl-2,3-dihydro-4H-1,2,4-benzothiadiazin-4-yl 1,1-dioxide)methyl]-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,...More Detail

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