Loratadine is a second-generation antihistamine widely used to relieve symptoms of allergic rhinitis and chronic urticaria without causing significant drowsiness. It works by selectively blocking peripheral histamine H1 receptors, thereby reducing allergic responses. Ensuring the pharmaceutical purity of Loratadine is essential for maintaining its therapeutic effectiveness, patient safety, and adherence to regulatory standards. Impurity profiling is vital to detect and control any unwanted substances that may arise during manufacturing, storage, or degradation. Here are some of its known impurities listed below.
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Catalogue No : LORA-OCL-001
CAS No : N/A
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4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene-1-piperidinecarboxylic acid ethyl ester
4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene-1-piperidinecarboxylic acid ethyl ester
Catalogue No : LORA-OCL-002
CAS No : N/A
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Synonyms
8-Chloro-6,11-dihydro-11-(4-piperidylidene)-5H-benzo[5,6]cyclohepta[1,2-b] pyridine
8-Chloro-6,11-dihydro-11-(4-piperidylidene)-5H-benzo[5,6]cyclohepta[1,2-b] pyridine