Neostigmine Impurities

Neostigmine is a cholinesterase inhibitor commonly used in the management of myasthenia gravis, postoperative urinary retention, and to reverse the effects of non-depolarizing muscle relaxants after surgery. It works by blocking the breakdown of acetylcholine, thereby enhancing neuromuscular transmission. Ensuring the pharmaceutical purity of Neostigmine is essential for maintaining its safety, efficacy, and compliance with regulatory standards. Impurity profiling aids in detecting and controlling unwanted substances that may arise during synthesis, storage, or degradation. Here are some of its known impurities listed below.

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